Browsing by Author "Kobrlova, Tereza"
Now showing items 1-1 of 1
-
Investigation of new orexin 2 receptor modulators using in silico and in vitro methods
Janockova, Jana; Dolezal, Rafael; Nepovimova, Eugenie; Kobrlova, Tereza; Benkova, Marketa; Kuca, Kamil; Konecny, Jan; Mezeiova, Eva; Melikova, Michaela; Hepnarova, Vendula; Ring, Avi; Soukup, Ondrej; Korabecny, Jan (2018)The neuropeptides, orexin A and orexin B (also known as hypocretins), are produced in hypothalamic neurons and belong to ligands for orphan G protein-coupled receptors. Generally, the primary role of orexins is to act as ...